Engineering first-in-class decoys and rapid diagnostics to disarm harmful autoantibodies

Targeting Type I Interferon and Folate Receptor Autoantibodies to restore immune balance, protect pregnancies, and improve lifelong health.

What we do

Micoy Therapeutics develops therapeutics and companion diagnostics that target harmful autoantibodies. Our lead programs address autoantibodies against Type I Interferons, which weaken antiviral immunity, and against Folate Receptor alpha (FRα), which block folate transport and are linked to infertility, pregnancy loss, and neurodevelopmental disorders. We are creating safe “decoy” biologics and rapid blood tests to identify and neutralize these autoantibodies early.

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Identifying Harmful Autoantibodies

The immune system is meant to protect us from harm—but sometimes it turns against the body’s own essential molecules. Micoy Therapeutics is uncovering this hidden layer of immune dysfunction: autoantibodies that block critical biological pathways and quietly contribute to disease.

Our work bridges immunology, protein engineering, and diagnostic innovation to detect and neutralize these harmful antibodies. By combining rapid blood tests, we aim to identify risk early, restore balance, and prevent long-term health effects.

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The Future of our Science

At Micoy Therapeutics, we believe the future of medicine lies in understanding and correcting the immune system’s hidden errors. By uncovering how autoantibodies interfere with key biological pathways, we are developing tools to detect these disruptions early and design safe ways to neutralize them.

Folate Receptor Autoantibodies (FRAAs)

Folate is essential for cell growth, fertility, and brain development. Some people develop autoantibodies against the Folate Receptor alpha (FRα) — the protein responsible for transporting folate into cells. These FRAAs can block folate uptake even when blood levels appear normal, leading to infertility, pregnancy loss, and neurodevelopmental disorders.

Micoy is developing NeuroLume™, a rapid, finger-prick test that detects FRAAs in minutes. This easy-to-use tool will help clinicians identify at-risk individuals early and guide folate-based interventions to support reproductive and neurological health.

Type I Interferon Autoantibodies

Type I interferons are key immune molecules that protect against viral infections. In some individuals, autoantibodies against interferons can neutralize these natural defenses, increasing susceptibility to severe illness.

Micoy is developing diagnostic assays to detect these autoantibodies and therapeutic decoys that safely neutralize them, helping restore normal immune protection.

A Platform for Immune Health

Across both programs, Micoy is building a platform that links precision diagnostics with targeted therapeutics. Our mission is to reveal how autoantibodies shape human health—and to create practical solutions that restore balance and resilience across the lifespan.

Join our campaign

Micoy Therapeutics is seeking accredited investors to join us in developing decoy therapies and restore immune function.

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Brooklyn, NY 11226

© Micoy Therapeutics 2025. All rights reserved.

© Micoy Therapeutics 2024.

All rights reserved.